Characterization of learning and memory behaviors and the effects of metrifonate in the C57BL strain of mice.

@article{Ikonen1999CharacterizationOL,
  title={Characterization of learning and memory behaviors and the effects of metrifonate in the C57BL strain of mice.},
  author={Sami Ikonen and Bernard H. Schmidt and Paavo Riekkinen},
  journal={European journal of pharmacology},
  year={1999},
  volume={372 2},
  pages={117-26}
}
In the near future, a number of transgenic mouse models with neuropathological characteristics of Alzheimer's disease are expected to become widely available. It will be important to characterize their behavior in models for learning and memory. As a first step, we have characterized normal, medial septal-lesioned and hippocampal-lesioned C57BL mice, in different behavioral tests, i.e., water maze spatial navigation, Y-maze and passive avoidance behavior. These experiments were complemented by… CONTINUE READING