Characterization of intracellular aggregates using fluorescently-tagged polyglutamine-expanded androgen receptor

Abstract

Spinal bulbar muscular atrophy (SBMA) is a classic CAG-repeat neurodegenerative disease. It is caused by expansion of a polyglutamine (polyGln) tract in the androgen receptor (AR). Recent evidence has indicated a potential role for nuclear and cytoplasmic inclusions in the pathogenesis of these diseases. We have used blue and green fluorescently-tagged AR… (More)
DOI: 10.1007/BF03033265

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Cite this paper

@article{PanetRaymond2001CharacterizationOI, title={Characterization of intracellular aggregates using fluorescently-tagged polyglutamine-expanded androgen receptor}, author={Valerie Panet-Raymond and Bruce Gottlieb and Lenore K. Beitel and Hyman M. Schipper and Michael Timiansky and Leonard Pinsky and Mark Trifiro}, journal={Neurotoxicity Research}, year={2001}, volume={3}, pages={259-275} }