Characterization of insulin-like growth factor-I/somatomedin-C receptors on human keratinocyte monolayers.

@article{Misra1986CharacterizationOI,
  title={Characterization of insulin-like growth factor-I/somatomedin-C receptors on human keratinocyte monolayers.},
  author={Pragati Misra and Brian J. Nickoloff and Vera B. Morhenn and Raymond L. Hintz and Ron G. Rosenfeld},
  journal={The Journal of investigative dermatology},
  year={1986},
  volume={87 2},
  pages={264-7}
}
A membrane receptor for insulin on cultured human keratinocyte monolayers has recently been reported. It has also been established by previous investigators that the receptors for insulin and the somatomedin peptide, insulin-like growth factor-I/somatomedin-C (IGF-I), have similar oligomeric composition. However, these 2 receptors can be distinguished by their high affinity for their respective peptides. The present study was undertaken to identify and characterize IGF-I receptors on human… CONTINUE READING