Characterization of immunophenotypic aberrancies in 200 cases of B acute lymphoblastic leukemia.

@article{Seegmiller2009CharacterizationOI,
  title={Characterization of immunophenotypic aberrancies in 200 cases of B acute lymphoblastic leukemia.},
  author={Adam C. Seegmiller and Steven H. Kroft and Nitin J. Karandikar and Robert W Mckenna},
  journal={American journal of clinical pathology},
  year={2009},
  volume={132 6},
  pages={940-9}
}
Morphologic distinction of leukemic lymphoblasts in B acute lymphoblastic leukemia (B-ALL) from their nonneoplastic counterparts in bone marrow (hematogones) can be difficult. Thus, the presence of aberrant antigen expression detectable by flow cytometry may be critical for diagnosis of B-ALL and detection of minimal residual disease. The current study examined the immunophenotype of B-lineage leukemic lymphoblasts in 200 consecutive, unique, pretreatment patient specimens. We found that all… CONTINUE READING
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