Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region.

@article{Chen2001CharacterizationOH,
  title={Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region.},
  author={Y D Chen and Yu Hua Zhao and Y Peter Di and Reen Wu},
  journal={American journal of respiratory cell and molecular biology},
  year={2001},
  volume={25 5},
  pages={542-53}
}
Human mucin (MUC) 5B gene expression in human airway epithelium was studied in both tissue sections and cultures of tracheobronchial epithelial (TBE) cells. In situ hybridization demonstrated that MUC5B message was expressed mainly in the mucous cells of submucosal glands of normal human airway tissues. Nevertheless, an elevated MUC5B message level could be seen in surface goblet cells from patients with airway diseases and inflammation. Regardless of the airway tissue sources, MUC5B message… CONTINUE READING

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