Characterization of human mesenchymal stem cell-engineered cartilage: analysis of its ultrastructure, cell density and chondrocyte phenotype compared to native adult and fetal cartilage.

@article{Hillel2010CharacterizationOH,
  title={Characterization of human mesenchymal stem cell-engineered cartilage: analysis of its ultrastructure, cell density and chondrocyte phenotype compared to native adult and fetal cartilage.},
  author={Alexander T. Hillel and Janis M Taube and Toby C Cornish and Blanka Sharma and Marc K. Halushka and Edward F. McCarthy and Grover M. Hutchins and Jennifer H Elisseeff},
  journal={Cells, tissues, organs},
  year={2010},
  volume={191 1},
  pages={12-20}
}
The production of engineered cartilage from mesenchymal stem cells is a rapidly developing field. Potential applications include the treatment of degenerative joint disease as well as the treatment of traumatic and surgical bone injury. Prior to clinical application, however, further characterization of the morphology, ultrastructure, biocompatibility, and performance of the engineered tissue is warranted. To achieve this, human mesenchymal stem cells (hMSCs) were grown in vitro in pellet… CONTINUE READING

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