Characterization of human haptoglobin cDNAs coding for α2FSβ and α1Sβ variants

@article{Straten1984CharacterizationOH,
  title={Characterization of human haptoglobin cDNAs coding for $\alpha$2FS$\beta$ and $\alpha$1S$\beta$ variants},
  author={A. van der Straten and A. Herzog and T. Cabezón and A. Bollen},
  journal={FEBS Letters},
  year={1984},
  volume={168}
}
A human liver library, derived from a heterozygous (Hp2‐1) donor, has been used to isolate cDNA clones coding for the haptoglobin (Hp) α1Sβ and α2FSβ variants. DNA sequencing has shown that the two variants are identical except for the αF duplicated segment in Hp α2FSβ. Four nucleotide changes have been found between the phenotypically different F and S regions of the Hp α2 gene, resulting in an Asp,Lys/Asn,Glu substitution. 
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