Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

  title={Characterization of human embryonic stem cell lines by the International Stem Cell Initiative},
  author={Oluseun Adewumi and Behrouz Aflatoonian and Lars Ahrlund-Richter and Michal Sela Amit and Peter W. Andrews and Gemma Beighton and Paul A. Bello and Nissim Benvenisty and Lorraine S. Berry and Simon Bevan and Barak Blum and Justin Brooking and Kevin G Chen and Andre Boon-Hwa Choo and Gary A. Churchill and Marie Corbel and Ivan Damjanov and Jon S Draper and Petr Dvorak and Katarina Emanuelsson and Roland A. Fleck and Angela C. Ford and Karin Gertow and Marina Gertsenstein and Paul Gokhale and RebeccaS. Hamilton and Ale{\vs} Hampl and Lyn E. Healy and Outi Hovatta and Johan Hyllner and Marta P. Imreh and Joseph Itskovitz-Eldor and Jamie L Jackson and Jacqueline L Johnson and Mark Howard Jones and Kehkooi Kee and Benjamin L. King and Barbara B Knowles and Majlinda Lako and Franck Lebrin and Barbara S. Mallon and Daisy Manning and Yoav Mayshar and Ronald D. G. Mckay and Anna E. Michalska and Milla Mikkola and Masha Mileikovsky and Stephen L. Minger and Harry D. M. Moore and Christine L Mummery and Andras D Nagy and Norio Nakatsuji and Carmel O'brien and Steve Kah-Weng Oh and Cia Olsson and Timo Otonkoski and Kye-yoon Park and Robert Passier and Hema Doshi Patel and Minal Patel and Roger Pedersen and Martin F Pera and Marian S. Piekarczyk and Renee Reijo Pera and Benjamin Eithan Reubinoff and Allan J. Robins and Peter J Rugg-Gunn and Thomas C. Schulz and Henrik Semb and Eric S. Sherrer and Henrike Siemen and Glyn N. Stacey and Marija Mostarica Stojkovi{\'c} and Hirofumi Suemori and Jin Szatkiewicz and Tikva Turetsky and Timo Tuuri and Steineke van den Brink and Kristina Vintersten and Sanna Vuoristo and Dorien Ward and Thomas Allan Weaver and Lesley A Young and Weidong Zhang},
  journal={Nature Biotechnology},
The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression patterns for several markers of human embryonic stem cells. They expressed the glycolipid antigens SSEA3 and SSEA4, the keratan sulfate antigens TRA-1-60, TRA-1-81, GCTM2 and GCT343, and the protein antigens CD9, Thy1 (also known as CD90), tissue… CONTINUE READING

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