Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

  title={Characterization of human embryonic stem cell lines by the International Stem Cell Initiative},
  author={Oluseun Adewumi and B. Aflatoonian and L. Ahrlund-Richter and M. Amit and P. Andrews and G. Beighton and P. A. Bello and N. Benvenisty and L. Berry and S. Bevan and B. Blum and J. Brooking and K. Chen and A. Choo and G. Churchill and M. Corbel and I. Damjanov and Jon S Draper and P. Dvoř{\'a}k and Katarina Emanuelsson and R. Fleck and Angela Ford and K. Gertow and M. Gertsenstein and P. Gokhale and Rebecca S. Hamilton and A. Hampl and L. Healy and O. Hovatta and J. Hyllner and M. Imreh and J. Itskovitz-Eldor and J. Jackson and J. Johnson and M. Jones and Kehkooi Kee and B. King and B. Knowles and M. Lako and F. Lebrin and B. Mallon and D. Manning and Yoav Mayshar and R. Mckay and A. E. Michalska and M. Mikkola and Masha Mileikovsky and S. Minger and H. Moore and C. Mummery and A. Nagy and N. Nakatsuji and C. O’Brien and S. Oh and C. Olsson and T. Otonkoski and K. Park and R. Passier and H. Patel and M. Patel and R. Pedersen and M. Pera and M. Piekarczyk and R. A. Pera and B. Reubinoff and A. Robins and J. Rossant and P. Rugg-Gunn and T. C. Schulz and H. Semb and E. S. Sherrer and Henrike Siemen and G. Stacey and M. Stojkovi{\'c} and H. Suemori and J. Szatkiewicz and T. Turetsky and Timo Tuuri and S. van den Brink and K. Vintersten and S. Vuoristo and D. Ward and T. Weaver and L. Young and W. Zhang},
  journal={Nature Biotechnology},
  • Oluseun Adewumi, B. Aflatoonian, +82 authors W. Zhang
  • Published 2007
  • Medicine, Biology
  • Nature Biotechnology
  • The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression patterns for several markers of human embryonic stem cells. They expressed the glycolipid antigens SSEA3 and SSEA4, the keratan sulfate antigens TRA-1-60, TRA-1-81, GCTM2 and GCT343, and the protein antigens CD9, Thy1 (also known as CD90), tissue… CONTINUE READING

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