Characterization of human adipose tissue-resident hematopoietic cell populations reveals a novel macrophage subpopulation with CD34 expression and mesenchymal multipotency.

@article{Eto2013CharacterizationOH,
  title={Characterization of human adipose tissue-resident hematopoietic cell populations reveals a novel macrophage subpopulation with CD34 expression and mesenchymal multipotency.},
  author={Hitomi Eto and Hisako Ishimine and Kahori Kinoshita and Kanako Watanabe-Susaki and Harunosuke Kato and Kentaro Doi and Shinichiro Kuno and Akira Kurisaki and Kotaro Yoshimura},
  journal={Stem cells and development},
  year={2013},
  volume={22 6},
  pages={985-97}
}
Adipose tissue (AT) is composed of mature adipocytes and stromal vascular fraction (SVF) cells, including adipose stem/stromal cells (ASCs). We characterized hematopoietic cells residing in human nonobese AT by analyzing the SVF isolated from human lipoaspirates and peripheral blood (PB). Flow cytometry revealed that AT-resident hematopoietic cells consisted of AT-resident macrophages (ATMs) or lymphocytes with a negligible number of granulocytes. AT-resident lymphocytes were composed of helper… CONTINUE READING
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