Characterization of human T lymphocytes that express the C3b receptor.

  title={Characterization of human T lymphocytes that express the C3b receptor.},
  author={James G. Wilson and Thomas F. Tedder and Douglas T Fearon},
  journal={Journal of immunology},
  volume={131 2},
The presence of the C3b receptor (C3bR) on human peripheral blood T lymphocytes was recognized by the capacity of rabbit F(ab')2 anti-C3bR and tetramethylrhodamine isothiocyanate (TRITC)-conjugated goat F(ab')2 anti-rabbit F(ab')2 to stain 14.5 +/- 3.7% (mean +/- SEM; n = 5) of lymphocytes forming rosettes with sheep erythrocytes (E). The F(ab')2 anti-C3bR also blocked the capacity of peripheral blood lymphocytes stained with OKT11 to form rosettes with bovine E bearing C3b and… CONTINUE READING


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