Characterization of human Enah gene.

  title={Characterization of human Enah gene.},
  author={Lorena Urbanelli and Carlo Massini and Carla Emiliani and Antonio N. Orlacchio and Giorgio Bernardi and Aldo Orlacchio},
  journal={Biochimica et biophysica acta},
  volume={1759 1-2},
Enabled homolog (Enah) is a mammalian ortholog of Drosophila Enabled (Ena), which is genetically linked to the Drosophila Abl tyrosine phosphorylation signaling cascade and is required for normal neural development. Vertebrates have three Ena-related genes: Enah, VASP (vasodilator-stimulated phosphoprotein) and Ena/VASP like (EVL). These genes play an important role in linking signal transduction pathways to localized remodeling of the actin cytoskeleton. We isolated and sequenced a cDNA… CONTINUE READING


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