Characterization of histamine H1-receptor on rat hepatocytes.

@article{Tsuchie1987CharacterizationOH,
  title={Characterization of histamine H1-receptor on rat hepatocytes.},
  author={Kenji Tsuchie and Masaya Imoto and Mieko Tanaka and Morimitsu Nishikimi and Yuji Nimura and Shigehiko Shionoya and Yoshiyuki Koyama and Takayuki Ozawa},
  journal={Biochemistry international},
  year={1987},
  volume={15 4},
  pages={719-26}
}
The binding sites for [3H]pyrilamine in isolated rat hepatocytes were characterized. Scatchard analysis revealed two kinds of binding sites in hepatocytes, a high-affinity site and a low-affinity one. The rates of binding of the radioligand with the high-affinity binding site and its dissociation were rapid. The specificity of the sites for various… CONTINUE READING