Characterization of hepatitis C virus deletion mutants circulating in chronically infected patients.

Abstract

Hepatitis C virus (HCV) has a linear positive-stranded RNA genome of approximately 9,600 nucleotides in length and displays a high level of sequence diversity caused by high mutation rates and recombination. However, when we performed long distance reverse transcription-PCRs on HCV RNA isolated from serum of chronic HCV patients, not only full-length HCV… (More)

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@article{Noppornpanth2007CharacterizationOH, title={Characterization of hepatitis C virus deletion mutants circulating in chronically infected patients.}, author={Suwanna Noppornpanth and Saskia L. Smits and Truong Thi Xuan Lien and Yong Poovorawan and Albert D M E Osterhaus and Bart L Haagmans}, journal={Journal of virology}, year={2007}, volume={81 22}, pages={12496-503} }