Characterization of hepatitis B virus (HBV) preS/S gene mutations in blood donors with occult HBV infection in the Baoji area of North China.

@article{Liao2017CharacterizationOH,
  title={Characterization of hepatitis B virus (HBV) preS/S gene mutations in blood donors with occult HBV infection in the Baoji area of North China.},
  author={Hao Liao and Yan Liu and Jianhong Chen and Weiping Ding and Xue Li and Zhihui Xu and Yuan Yang and Rongjuan Chen and Lanlan Si and Xiaoyuan Xu and Jianxun Guo and Dongping Xu},
  journal={Transfusion},
  year={2017},
  volume={57 3pt2},
  pages={857-866}
}
BACKGROUND Occult hepatitis B virus (HBV) infection (OBI) in blood donors was investigated in the Baoji area of North China, and OBI-related viral mutations in donors were characterized. STUDY DESIGN AND METHODS In total, 110,843 blood donor samples that were consecutively collected from December 2011 to March 2015 at the Baoji Blood Center were examined. Hepatitis B surface antigen-negative and HBV DNA-positive OBI samples were amplified for sequence analysis of OBI-related mutations in the… CONTINUE READING