Characterization of glycol chitosan grafted with low molecular weight polyethylenimine as a gene carrier for human adipose-derived mesenchymal stem cells.

@article{Bae2016CharacterizationOG,
  title={Characterization of glycol chitosan grafted with low molecular weight polyethylenimine as a gene carrier for human adipose-derived mesenchymal stem cells.},
  author={Yoonhee Bae and Young Hwa Lee and Sunray Lee and Jin Han and Kyung Soo Ko and Joon Sig Choi},
  journal={Carbohydrate polymers},
  year={2016},
  volume={153},
  pages={
          379-390
        }
}
Mesenchymal stem cells (MSCs) have a great capacity for self-renewal while still maintaining their multipotency, and can differentiate into a variety of cell types. The delivery of genes to a site of injury is a current and interesting field of gene therapy. In the present study, we describe a nonviral gene delivery carrier, glycol chitosan-methyl acrylate-polyethylenimine (GMP) polymer targeted towards human adipose-derived mesenchymal stem cells (AD-MSCs). Transfection efficiency, using… CONTINUE READING
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