Characterization of genetic defects of hemophilia A in mainland China.

Abstract

Southern blotting, PCR, DGGE and DNA sequencing were used to study gene mutations in 52 unrelated Chinese Hemophilia A patients. 18 out of 34 severe cases had intron 22 inversions, 13 had small gene lesions, of which five are novel.

Cite this paper

@article{Zhang1999CharacterizationOG, title={Characterization of genetic defects of hemophilia A in mainland China.}, author={Y. Z. Zhang and Jianxin Liu and Hui Shao and Z W Chi and H - C . Li L . Wang and S Chen and Chen Zhi and Zheng Wang and W H Huang}, journal={Genetic analysis : biomolecular engineering}, year={1999}, volume={15 6}, pages={205-7} }