Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos).

@article{Borrero2011CharacterizationOG,
  title={Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos).},
  author={Juan Borrero and Dag Anders Brede and Morten Skaugen and Dzung Bao Diep and Carmen Rosa Herranz and Ingolf F. Nes and Luis Mar{\'i}a Cintas and Pablo V. Hernandez},
  journal={Applied and environmental microbiology},
  year={2011},
  volume={77 1},
  pages={369-73}
}
Lactococcus garvieae DCC43 produces a bacteriocin, garvicin ML (GarML), with a molecular mass of 6,004.2 Da. Data from de novo amino acid sequencing by tandem mass spectrometry and nucleotide sequencing by reverse genetics suggested that the bacteriocin is synthesized as a 63-amino-acid precursor with a 3-amino-acid leader peptide that is removed by cleavage. Subsequently, a covalent linkage between the N and C termini forms the mature version of this novel 60-amino-acid circular bacteriocin. 

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