Characterization of foot-and-mouth disease virus by monoclonal antibodies.

@article{Alonso1993CharacterizationOF,
  title={Characterization of foot-and-mouth disease virus by monoclonal antibodies.},
  author={Agust{\'i}n Tom{\'a}s Vega Alonso and Mogar Dreon Gomes and A K Ramalho and Rossana Allende and H Barahona and Magnus S. S{\"o}ndahl and Fernando Abel Osorio},
  journal={Viral immunology},
  year={1993},
  volume={6 3},
  pages={
          219-28
        }
}
Monoclonal antibodies (MAbs) were produced against foot-and-mouth disease (FMD) virus types O1 Campos Br1/58, A24 Cruzeiro Br1/55, and C3 Indaial Br1/71, which are the strains used for production of FMD vaccines in the majority of South American countries. Within the library of MAbs produced, a group was selected on the basis of their neutralizing titer in cell culture, protective titer in suckling mice, sensitivity to trypsin, and specificity for virus structural proteins. The MAbs were… CONTINUE READING

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