Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.

Abstract

Sialic acid-binding immunoglobulin-like lectin (Siglec)-F, an inhibitory receptor on mouse eosinophils, preferentially recognizes the glycan ligand 6'-sulfated sialyl Lewis X, but little is known about the requirements for its lung expression. RT-PCR and immunohistochemistry were used to detect and localize the sulfotransferase keratin sulfate galactose 6-O… (More)
DOI: 10.1165/rcmb.2010-0007OC

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