Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.

@article{Kesimer2009CharacterizationOE,
  title={Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.},
  author={Mehmet Kesimer and Margaret A Scull and Brian K. Brighton and Genevieve DeMaria and Kimberlie A. Burns and Wanda O'neal and Raymond J. Pickles and John Kieran Sheehan},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2009},
  volume={23 6},
  pages={
          1858-68
        }
}
Airway mucus forms the structural basis of the local innate immune defense mechanism. It is an integrated, active, viscoelastic gel matrix evolved to protect the exposed lung from physical, chemical, and pathological erosion. Exosomes are biologically active vesicles secreted by different cell types including epithelial, hematopoietic, and some tumor cells. They are also present in some biological fluids such as serum, urine, breast milk, and bronchoalveolar lavage fluid. In this study, we… CONTINUE READING

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