Characterization of exogenous proviral sequences in hamster tumor cell lines transformed by Rous sarcoma virus rescued from XC cells.

@article{Svoboda1983CharacterizationOE,
  title={Characterization of exogenous proviral sequences in hamster tumor cell lines transformed by Rous sarcoma virus rescued from XC cells.},
  author={Jan Svoboda and Vladimir Lhotak and Josef Geryk and Simon Saule and M B Raes and Dominique St{\'e}helin},
  journal={Virology},
  year={1983},
  volume={128 1},
  pages={195-209}
}
Alterations in viral structural genes have been studied in five cell lines derived from Syrian hamster tumors which had been induced by the virus rescued from XC cells by transfection. Two cell lines, H-18 and H-20, have all the viral structural genes expressed, but a new EcoRI recognition site appeared in the region of the pol gene sequence. Provirus present in H-12 lacks the 3' part of the gag gene sequences as well as the pol gene, therefore, it gives rise to an anomalous 1.8 Md EcoRI… CONTINUE READING
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