Characterization of drug-release kinetics in trabecular bone from titania nanotube implants

@inproceedings{Aw2012CharacterizationOD,
  title={Characterization of drug-release kinetics in trabecular bone from titania nanotube implants},
  author={Moom Sinn Aw and Kamarul A Khalid and Karan Gulati and Gerald James Atkins and Peter Pivonka and David M. Findlay and Dusan Losic},
  booktitle={International journal of nanomedicine},
  year={2012}
}
PURPOSE The aim of this study was to investigate the application of the three-dimensional bone bioreactor for studying drug-release kinetics and distribution of drugs in the ex vivo cancellous bone environment, and to demonstrate the application of nanoengineered titanium (Ti) wires generated with titania nanotube (TNT) arrays as drug-releasing implants for local drug delivery METHODS Nanoengineered Ti wires covered with a layer of TNT arrays implanted in bone were used as a drug-releasing… CONTINUE READING
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