Characterization of drug interactions with serum proteins by using high-performance affinity chromatography.

Abstract

The binding of drugs with serum proteins can affect the activity, distribution, rate of excretion, and toxicity of pharmaceutical agents in the body. One tool that can be used to quickly analyze and characterize these interactions is high-performance affinity chromatography (HPAC). This review shows how HPAC can be used to study drug-protein binding and… (More)

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Cite this paper

@article{Hage2011CharacterizationOD, title={Characterization of drug interactions with serum proteins by using high-performance affinity chromatography.}, author={David S Hage and Jeanethe A Anguizola and Omar S Barnaby and Abby Jo Jackson and Michelle Ji Yeon Yoo and Efthimia Papastavros and Erika L. Pfaunmiller and Matt Sobansky and Zenghan Tong}, journal={Current drug metabolism}, year={2011}, volume={12 4}, pages={313-28} }