Characterization of distinct angiotensin II binding sites in rat adrenal gland and bovine cerebellum using selective nonpeptide antagonists.

Abstract

We investigated the characteristics of 125I-AII binding to rat adrenal and bovine cerebellar membranes in the presence and absence of new nonpeptide angiotensin II (AII) receptor ligands. The imidazole AII ligands, DUP753 and WL19, both produced biphasic competition curves to 125I-AII binding in rat adrenal glomerulosa and adrenal medulla particles… (More)

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@article{Wiest1991CharacterizationOD, title={Characterization of distinct angiotensin II binding sites in rat adrenal gland and bovine cerebellum using selective nonpeptide antagonists.}, author={Sally A. Wiest and Andy Rampersaud and Kathy A. Zimmerman and Malcolm Steinberg}, journal={Journal of cardiovascular pharmacology}, year={1991}, volume={17 2}, pages={177-84} }