Characterization of distamycin A binding to damaged DNA.

Abstract

We previously reported that distamycin A, a natural antibiotic known as a minor groove binder, could bind to DNA duplexes containing the (6-4) photoproduct formed at its target site, whereas the binding was not observed for duplexes containing the cis-syn cyclobutane pyrimidine dimer in the same sequence context. In this study, we have further analyzed the… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.