Characterization of discriminatory urinary proteomic biomarkers for severe preeclampsia using SELDI-TOF mass spectrometry.

@article{Lee2011CharacterizationOD,
  title={Characterization of discriminatory urinary proteomic biomarkers for severe preeclampsia using SELDI-TOF mass spectrometry.},
  author={Seung Mi Lee and Joong Shin Park and Errol R. Norwitz and Sun Min Kim and Byoung Jae Kim and Chan-Wook Park and Jong Kwan Jun and Hee Chul Syn},
  journal={Journal of perinatal medicine},
  year={2011},
  volume={39 4},
  pages={391-6}
}
OBJECTIVE To analyze the proteomic pattern in urine for distinguishing severe preeclampsia from mild preeclampsia and normotensive controls using surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF-MS). STUDY DESIGN Urine samples were collected from women with severe preeclampsia (n=11 [sPE]), mild preeclampsia (n=7 [mPE]), and normotensive controls (n=8) and analyzed by SELDI-TOF-MS to identify discriminatory protein peaks in the sPE cohort. A scoring… CONTINUE READING

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