Characterization of dexamethasone-induced reactivation of latent bovine herpesvirus 1.

  title={Characterization of dexamethasone-induced reactivation of latent bovine herpesvirus 1.},
  author={Daquarii Rock and James R Lokensgard and Taiesha Lewis and Gerald F. Kutish},
  journal={Journal of virology},
  volume={66 4},
Synchronous reactivation of bovine herpesvirus type 1 in all latently infected rabbits was achieved following a single intravenous dose of dexamethasone. Reactivated latent virus was first present in ocular secretions between 48 and 72 h post-dexamethasone treatment (PT). Cell-free infectious virus, viral-antigen-containing neurons, and pathologic changes were detectable in trigeminal ganglia (TG) by 48 h PT. A shift from the viral transcriptional pattern characteristic of the latent state… CONTINUE READING
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Analysis of the transcriptional promoter which regulates the latency - related transcript of bovine herpesvirus 1

  • R. F. Kahrs
  • J . Virol .
  • 1990

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