Characterization of dSnoN and its relationship to Decapentaplegic signaling in Drosophila.

@article{Barrio2007CharacterizationOD,
  title={Characterization of dSnoN and its relationship to Decapentaplegic signaling in Drosophila.},
  author={Rosa Barrio and Ana L{\'o}pez-Varea and Mar Casado and Jose F de Celis},
  journal={Developmental biology},
  year={2007},
  volume={306 1},
  pages={66-81}
}
Vertebrate members of the ski/snoN family of proto-oncogenes antagonize TGFbeta and BMP signaling in a variety of experimental situations. This activity of Ski/SnoN proteins is related to their ability to interact with Smads, the proteins acting as key mediators of the transcriptional response to the TGFbeta superfamily members. However, despite extensive efforts to identify the physiological roles of the Ski/SnoN proteins, it is not yet clear whether they participate in regulating Activin and… CONTINUE READING

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