Characterization of cyanobacterial β‐carotene ketolase and hydroxylase genes in Escherichia coli, and their application for astaxanthin biosynthesis

@article{Scaife2009CharacterizationOC,
  title={Characterization of cyanobacterial $\beta$‐carotene ketolase and hydroxylase genes in Escherichia coli, and their application for astaxanthin biosynthesis},
  author={M. A. Scaife and A. Burja and P. Wright},
  journal={Biotechnology and Bioengineering},
  year={2009},
  volume={103}
}
Carotenoid biosynthesis is highly conserved and well characterized up to the synthesis of β‐carotene. Conversely, the synthesis of astaxanthin from β‐carotene is less well characterized. Regardless, astaxanthin is a highly sought natural product, due to its various industrial applications and elevated antioxidant capacity. In this article, 12 β‐carotene ketolase and 4 β‐carotene hydroxylase genes, isolated from 5 cyanobacterial species, are investigated for their function, and potential for… Expand
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