Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs.

  title={Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs.},
  author={D. T. Hamamoto and D. Simone},
  journal={Journal of neurophysiology},
  volume={90 2},
  • D. T. Hamamoto, D. Simone
  • Published 2003
  • Medicine, Psychology
  • Journal of neurophysiology
  • Acetic acid applied to the hind limb of a frog evokes nocifensive behaviors, including a vigorous wiping of the exposed skin, referred to as the wiping response. The aim of this study was to examine the responses of cutaneous primary afferent fibers in frogs to acetic acid (pH 2.84-1.42) applied topically to the skin. Conventional electrophysiological methods were used to record neuronal activity from single identified primary afferent fibers with cutaneous receptive fields on the hind limb… CONTINUE READING
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    Publications referenced by this paper.
    Excitation by irritant chemical substances of sensory afferent units in the cat's cornea.
    • 210
    Responses of cutaneous A-fiber nociceptors to noxious cold.
    • 193
    • PDF
    Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro
    • 480
    • Highly Influential
    • PDF
    Unresponsive afferent nerve fibres in the sural nerve of the rat.
    • 166
    Some properties of frog skin mechanoreceptors
    • 47
    • Highly Influential
    Excitation of rat cutaneous nociceptors by noxious cold
    • 103
    A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro
    • 253
    • Highly Influential
    • PDF
    Cutaneous sensory receptors in the rat foot.
    • 376
    Cellular mechanisms of nociception in the frog.
    • 15
    • Highly Influential
    • PDF