Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs.

  title={Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs.},
  author={D. T. Hamamoto and D. Simone},
  journal={Journal of neurophysiology},
  volume={90 2},
  • D. T. Hamamoto, D. Simone
  • Published 2003
  • Medicine, Psychology
  • Journal of neurophysiology
  • Acetic acid applied to the hind limb of a frog evokes nocifensive behaviors, including a vigorous wiping of the exposed skin, referred to as the wiping response. The aim of this study was to examine the responses of cutaneous primary afferent fibers in frogs to acetic acid (pH 2.84-1.42) applied topically to the skin. Conventional electrophysiological methods were used to record neuronal activity from single identified primary afferent fibers with cutaneous receptive fields on the hind limb… CONTINUE READING
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