Characterization of cortical neuron outgrowth in two- and three-dimensional culture systems.

  title={Characterization of cortical neuron outgrowth in two- and three-dimensional culture systems.},
  author={Po-Wei Lin and Chi-Chen Wu and Chien-Ho Chen and H Ho and Yi-chun Chen and M J Sheu},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={75 1},
To improve the ability of regeneration by grafting living cells or by adding growth factor to a lesion site, it is important to find good biomaterials for neuron survival and regeneration. This study focused on two- and three-dimensional cultures in a matrix using biomaterials such as agarose, collagen, fibrin, and their mixtures, because these are considered to be suitable biomaterials for neuron outgrowth. Cortical neurons were dissected from E17 rat embryos and cultured in agarose gel… CONTINUE READING

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