Characterization of collagens and proteoglycans at the insertion of the human Achilles tendon.

@article{Waggett1998CharacterizationOC,
  title={Characterization of collagens and proteoglycans at the insertion of the human Achilles tendon.},
  author={Andrew D. Waggett and Jim R. Ralphs and Alvin P. L. Kwan and David John Woodnutt and Mike Benjamin},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={1998},
  volume={16 8},
  pages={457-70}
}
This study provides a unique correlation between a molecular biological and biochemical analysis of the extracellular matrix (ECM) macromolecules in one half of 28 human Achilles tendons with an immunohistochemical study of the other. Both the insertion site and the mid-tendon were studied. The insertion (enthesis) is characterized by three distinctive fibrocartilages, two in the tendon (enthesial and sesamoid) and one on the heel bone (periosteal). Thus, its structure contrasts markedly with… CONTINUE READING

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