Characterization of clarithromycin resistance in isolates of Helicobacter pylori from the UAE.

  title={Characterization of clarithromycin resistance in isolates of Helicobacter pylori from the UAE.},
  author={Mubarak Saif Alfaresi and Abida A Elkoush},
  journal={Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology},
  volume={29 3},
BACKGROUND Clarithromycin therapy is effective in eradicating Helicobacter pylori. However, the resistance of H. pylori to clarithromycin is increasingly reported. The present study aimed to characterize the types of mutations present in the 23S rRNA genes of isolates of clarithromycin-resistant H. pylori from the UAE. METHODS Clarithromycin susceptibility of H. pylori isolates (n = 26) was determined by E tests. Analyses for point mutations in domain V of the 23S rRNA genes in clarithromycin… CONTINUE READING

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