Characterization of chromatin structure by image analysis--a method for the assessment of changes in chromatin organization.

@article{Danielsen1989CharacterizationOC,
  title={Characterization of chromatin structure by image analysis--a method for the assessment of changes in chromatin organization.},
  author={H{\aa}vard E. Danielsen and George W. Farrants and Albrecht Reith},
  journal={Scanning microscopy. Supplement},
  year={1989},
  volume={3},
  pages={297-302}
}
This paper describes an image analysis technique for the assessment of changes in chromatin organization in ultrathin tissue sections. Transmission electron micrographs of tissue sections were analyzed by a SEM-IPS image processing unit (Kontron) at a total magnification of 7,500. The boundaries of each nucleus and each nucleolus were defined interactively… CONTINUE READING