Characterization of chloride channels in membrane vesicles from the kidney outer medulla

The basolateral membrane of the thick ascending loop of Henle (TALH) of the mammalian kidney is highly enriched in Na+/K+ ATPase and has been shown by electrophysiological methods to be highly conductive to Cl−. In order to study the Cl− conductive pathways, membrane vesicles were isolated from the TALH-containing region of the porcine kidney, the red outer… CONTINUE READING