Characterization of chitosan acetate as a binder for sustained release tablets.

@article{Nunthanid2004CharacterizationOC,
  title={Characterization of chitosan acetate as a binder for sustained release tablets.},
  author={Jurairat Nunthanid and M Laungtana-Anan and Pornsak Sriamornsak and Sontaya Limmatvapirat and Satit Puttipipatkhachorn and Lee Yong Lim and E. W. Khor},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2004},
  volume={99 1},
  pages={15-26}
}
A chitosan derivative as an acetate salt was successfully prepared by using a spray drying technique. Physicochemical characteristics and micromeritic properties of spray-dried chitosan acetate (SD-CSA) were studied as well as drug-polymer and excipient-polymer interaction. SD-CSA was spherical agglomerates with rough surface and less than 75 microm in diameter. The salt was an amorphous solid with slight to moderate hygroscopicity. The results of Fourier transform infrared (FTIR) and solid… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Manufacture of chitosan and chitin porous microparticles

  • H. Yabe, M. Itoyama, Y. Kawamura
  • J.P. Patent, JP 632210101 A2, Aug. 31, 1988. J…
  • 2004

In vitro evaluation of matrix granules containing microcrystalline chitosan as a gel forming excipient

  • T. Cerchiara Orienti, B. Luppi, F. Bigucci, G. Zuccari, V. Zecchi
  • Int . J . Pharm .
  • 2003

Marvola, In vitro evaluation of matrix granules containing microcrystalline chitosan as a gel forming excipient

  • M. S7kkinen, A. Linna, S. Ojala, H. Jqrjenson, M. P. Veski
  • Int. J. Pharm
  • 2003

Powders containing high concentration of chitosan and their manufacture

  • T. Kawaguchi, H. Maeda
  • J.P. Patent, JP 2003047435 A2, Feb. 18
  • 2003

Characterization of chitin , chitosan and their carboxymethyl derivatives by differential scanning calorimetry

  • T. F. Moura Santos, F. N. Raffin
  • Carbohydr . Polym .
  • 2002

Effect of spray drying conditions on the morphology of chitosan microspheres for protein delivery

  • J. V. Santos, T. F. Moura, F. N. Raffin
  • International Pharmaceutical Federation World…
  • 2002

Similar Papers

Loading similar papers…