Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

@article{Zhang2002CharacterizationOC,
  title={Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.},
  author={Weilie Zhang and Anthony S. Basile and Jes{\'u}s Gomeza and Laura A Volpicelli and Allan I. Levey and Juergen Wess},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 5},
  pages={1709-17}
}
Forebrain muscarinic acetylcholine (ACh) receptors (mAChRs; M1-M5) are predicted to play important roles in many fundamental central functions, including higher cognitive processes and modulation of extrapyramidal motor activity. Synaptic ACh levels are known to be regulated by the activity of presynaptic muscarinic autoreceptors mediating inhibition of ACh release. Primarily because of the use of ligands with limited receptor subtype selectivity, classical pharmacological studies have led to… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
104 Citations
56 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 104 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Similar Papers

Loading similar papers…