Characterization of central and peripheral components of the hypothalamus–pituitary–adrenal axis in the inbred Roman rat strains

@article{Carrasco2008CharacterizationOC,
  title={Characterization of central and peripheral components of the hypothalamus–pituitary–adrenal axis in the inbred Roman rat strains},
  author={Javier Carrasco and Cristina M{\'a}rquez and Roser Nadal and Adolfo Tobe{\~n}a and Antonio Armario},
  journal={Psychoneuroendocrinology},
  year={2008},
  volume={33},
  pages={437-445}
}
Several studies performed in outbred Roman high- and low-avoidance lines (RHA and RLA, respectively) have demonstrated that the more anxious line (RLA) is characterized by a higher hypothalamic-pituitary-adrenal (HPA) response to certain stressors than the less anxious one (RHA). However, inconsistent results have also been reported. Taking advantage of the generation of an inbred colony of RLA and RHA rats (RHA-I and RLA-I, respectively), we have characterized in the two strains not only… CONTINUE READING

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