Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro.

@article{Waldman2002CharacterizationOC,
  title={Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro.},
  author={Stephen D. Waldman and Marc D. Grynpas and Robert M. Pilliar and Rita A Kandel},
  journal={Journal of biomedical materials research},
  year={2002},
  volume={62 3},
  pages={323-30}
}
Successful joint resurfacing by tissue-engineered cartilage has been limited, in part, by an inability to secure the implant to bone. To overcome this, we have developed the methodology to form a cartilage implant in vitro consisting of a layer of cartilagenous tissue overlying a porous, biodegradable calcium polyphosphate (CPP) substrate. As bone will grow into the CPP after implantation, it will result in anchorage of the cartilage. In this study, the cartilagenous tissue formed in vitro… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

Similar Papers

Loading similar papers…