Characterization of calpastatin gene in fish: its potential role in muscle growth and fillet quality.

@article{Salem2005CharacterizationOC,
  title={Characterization of calpastatin gene in fish: its potential role in muscle growth and fillet quality.},
  author={Mohamed Salem and Jianbo Yao and Caird E. Rexroad and Patrick Brett Kenney and Kenneth Semmens and John Killefer and Joginder Nath},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2005},
  volume={141 4},
  pages={488-97}
}
Calpastatin (CAST), the specific inhibitor of the calpain proteases, plays a role in muscle growth and meat quality. In rainbow trout (RBT), we identified cDNAs coding for two CAST isoforms, a long (CAST-L) and a short isoform (CAST-S), apparently derived from two different genes. Zebrafish and pufferfish CAST cDNA and genomic sequences were retrieved from GenBank and their exon/intron structures were characterized. Fish CASTs are novel in that they have fewer repetitive inhibitory domains as… CONTINUE READING

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