Characterization of calcitonin gene-related peptide (CGRP) receptors in guinea pig basilar artery.

Abstract

The vasomotor effects of calcitonin gene-related peptide (CGRP) analogs have been studied in circular segments of guinea pig basilar artery in vitro. Five CGRP agonists induced concentration-dependent relaxations of pre-contracted vessels with the following order of potency: alpha-rCGRP greater than or equal to beta-rCGRP greater than or equal to alpha… (More)

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