Characterization of cDNAs encoding the murine A+U-rich RNA-binding protein AUF1.


A+U-rich elements (ARE) serve to control the degradation of some proto-oncogene and lymphokine mRNAs. The protein, AUF1, which consists of two polypeptides of 37 and 40 kDa (p37 and p40, respectively) when purified from cytosol, has been implicated in ARE-directed mRNA turnover due to its binding to ARE. Molecular cloning of a cDNA (p37AUF1) corresponding… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.