Characterization of cDNAs encoding adhesin proteins involved in trichomonas vaginalis cytoadherence.

@article{Arroyo1995CharacterizationOC,
  title={Characterization of cDNAs encoding adhesin proteins involved in trichomonas vaginalis cytoadherence.},
  author={Rossana Arroyo and Jean A. Engbring and Jimmy Nguyen and Oxana Musatovova and Osvaldo I Lopez and Crystal M. Lauriano and John F. Alderete},
  journal={Archives of medical research},
  year={1995},
  volume={26 4},
  pages={361-9}
}
Trichomonas vaginalis cytoadherence is mediated by four adhesins (AP65, AP51, AP33 and AP23). Adhesin gene expression was previously shown to be up-regulated by iron. Therefore, a cDNA library was constructed from mRNA of T. vaginalis grown in a high-iron medium. Ten cDNA clones (three for AP65, one for AP51, and six for AP33) were recognized with polyclonal antiserum or monoclonal antibody raised against these adhesins. No cross-hybridization among cDNAs of the three adhesins was observed in… CONTINUE READING

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