Characterization of bradykinin-induced endothelium-independent contraction in equine basilar artery.

Abstract

We investigated the effect of bradykinin (BK) on isolated equine basilar arterial rings with and without endothelium. BK induced concentration-dependent contraction of resting arterial rings and no relaxation when the rings were precontracted by prostaglandin F(2alpha). The maximal response and pD(2) value were 161.2 +/- 28.1% (to 60 mm KCl-induced… (More)
DOI: 10.1111/j.1365-2885.2008.01037.x

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