Characterization of beta-adrenoreceptors of rainbow trout (Oncorhynchus mykiss) erythrocytes.

  title={Characterization of beta-adrenoreceptors of rainbow trout (Oncorhynchus mykiss) erythrocytes.},
  author={Scott D. Reid and Thomas Moon and Steve F. Perry},
  journal={The Journal of experimental biology},
Although many studies have characterized these receptors according to pharmacological criteria, this work represents only the second direct characterization of the rainbow trout beta-adrenergic receptors. Radioligand binding assays using (+/-)-4-(3-t-butylamino-2-hydroxy-propoxy)-[5,7-3H]benzimidazol-2- one ([3H]CGP 12177) and 1-[4,6-propyl 3H]dihydroalprenolol ([3H]DHA) were conducted to determine equilibrium binding times, ligand-receptor dissociation constants (KD) and binding capacities… CONTINUE READING
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