Characterization of attenuation and respiratory motion artifacts and their influence on SPECT MP image evaluation using a dynamic phantom assembly with variable cardiac defects

  title={Characterization of attenuation and respiratory motion artifacts and their influence on SPECT MP image evaluation using a dynamic phantom assembly with variable cardiac defects},
  author={Isabelle Chrysanthou-Baustert and I. Polycarpou and O. Demetriadou and L. Livieratos and A. Lontos and A. Antoniou and S. Christofides and C. Yiannakkaras and D. Kaolis and Christoforos Panagidis and P. Marsden and Y. Parpottas},
  journal={Journal of Nuclear Cardiology},
BackgroundA phantom assembly that simulates the respiratory motion of the heart was used to investigate artifacts and their impact on defect detection.MethodsSPECT/CT images were acquired for phantoms with and without small and large cardiac defects during normal and deep breathing, and also at four static respiratory phases. Acquisitions were reconstructed with and without AC, and with misalignment of transmission and emission scans. A quantitative analysis was performed to assess artifacts… Expand
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A sophisticated anthropomorphic thorax phantom is presented that combines several aspects of a simulator for cardio-respiratory motion and is constructed to be MR-compatible, which means it can not only perform studies in PET, SPECT and CT, but also inside an MRI system. Expand
Have SPECT artifacts breathed their last?
  • C. Hansen
  • Medicine
  • Journal of Nuclear Cardiology
  • 2016
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Effect of respiratory motion in CT-based attenuation correction in SPECT using different CT scanners and protocols
  • W. Segars, B. Tsui
  • Physics, Medicine
  • IEEE Nuclear Science Symposium Conference Record, 2005
  • 2005
It is concluded that respiratory motion is an important consideration in SPECT-CT imaging when using CT-based AC, and careful work must be done to design protocols to reduce CT artifacts while minimizing the mismatch between the CT and SPECT data. Expand
Effect of mechanically simulated diaphragmatic respiratory motion on myocardial SPECT processed with and without attenuation correction.
The results support a clinical need for respiratory gating of myocardial SPECT images and support the ability of attenuation correction (AC) to correct for this artifact in the presence of diaphragmatic motion. Expand
Evaluation of Respiratory Motion Effect on Defect Detection in Myocardial Perfusion SPECT: A Simulation Study
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Comparison of methods of acquiring attenuation maps for cardiac SPECT in the presence of respiratory motion
The CBCT approach resulted in the best uniformity of the AC emission images, and phantom respiratory motion reduced the AI/LS ratio compared to when the phantoms were stationary. Expand
Effects of misalignment between transmission and emission scans on attenuation-corrected cardiac SPECT.
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CT-based AC of SPECT images consistently improved overall diagnostic performance of readers with different interpretive attitudes and experience, and is well suited for routine use in clinical practice. Expand
Attenuation correction of myocardial SPECT studies using low resolution computed tomography images
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There are a number of factors that affect the intensity of the apical region in cardiac SPECT images, which sometime lead to apparent defects in this region. In some patient studies, imagesExpand
Diagnostic sensitivity of SPECT myocardial perfusion imaging using a pumping cardiac phantom with inserted variable defects
The diagnostic sensitivity of SPECT MPI procedures was improved when applying AC or GSPECT techniques to identify subendocardial defects in the inferior, anterior and apical segments of the myocardial wall of the left ventricle for all three body types. Expand
Attenuation Correction in Myocardial Perfusion SPECT/CT: Effects of Misregistration and Value of Reregistration
Reregistration of misalignment significantly affected regional radiotracer distribution in the segments shown to be influenced by misregistration, which influences regional tracer distribution on attenuation-corrected myocardial images. Expand