Characterization of aspartame-cyclodextrin complexation.


The inclusion complex formation of aspartame (guest) and various cyclodextrins (host) were examined using 1H NMR titration and capillary electrophoresis. Initially the protonation constants of aspartame were determined by NMR-pH titration with in situ pH measurement to yield log K1=7.83 and log K2=2.96. Based on these values the stability of the complexes… (More)
DOI: 10.1016/j.jpba.2009.06.010


Cite this paper

@article{Sohajda2009CharacterizationOA, title={Characterization of aspartame-cyclodextrin complexation.}, author={Tam{\'a}s Sohajda and Szabolcs B{\'e}ni and Erzs{\'e}bet Varga and R{\'o}bert Iv{\'a}nyi and {\'A}kos R{\'a}cz and Lajos Szente and B{\'e}la Nosz{\'a}l}, journal={Journal of pharmaceutical and biomedical analysis}, year={2009}, volume={50 5}, pages={737-45} }