Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing by bovine alveolar neutrophils elicited with leukotriene B4 and zymo-san-activated plasma

@article{Heidel1991CharacterizationOA,
  title={Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing by bovine alveolar neutrophils elicited with leukotriene B4 and zymo-san-activated plasma},
  author={Jerry R. Heidel and Stephen M. Taylor and Ron M. Silflow and William W. Laegreid and R. Wes Leid},
  journal={Inflammation},
  year={1991},
  volume={15},
  pages={31-42}
}
Leukotriene B4 (LTB4) and zymosan-activated plasma (ZAP) were each instilled into the lungs of steers to elicit alveolar neutrophils for subsequent functional analysis. Prior to instillation of either agent, bronchoalveolar lavage cell populations consisted of 95.8 ± 0.4% macrophages (mean ±SEM). Four hours after instillation of LTB4 or ZAP, the lavage cell populations consisted of 75.0 ± 8.8% and 90.7 ± 0.7% neutrophils, respectively. Alveolar neutrophils elicited with LTB4 and stimulated with… CONTINUE READING
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