Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project.

@article{Higgins2008CharacterizationOA,
  title={Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project.},
  author={Anne W. Higgins and Fowzan S. Alkuraya and Amy Foster Bosco and Kerry K. Brown and Gail A. P. Bruns and Diana J. Donovan and Robert N Eisenman and Yanli Fan and Chantal G Farra and Heather L. Ferguson and James F. Gusella and David Harris and Steven R. Herrick and Chantal Kelly and Hyung-Goo Kim and Shotaro Kishikawa and Bruce R Korf and Shashikant Kulkarni and Eric Lally and Natalia T. Leach and E. Lemyre and Janine Lewis and Azra H. Ligon and Weining Lu and Richard L. Maas and Marcy E. MacDonald and Steven D P Moore and Roxanna E. Peters and Bradley J Quade and Fabiola Quintero-Rivera and Irfan Saadi and Yiping Shen and Jay Shendure and Robin E. Williamson and Cynthia C Morton},
  journal={American journal of human genetics},
  year={2008},
  volume={82 3},
  pages={
          712-22
        }
}
  • Anne W. Higgins, Fowzan S. Alkuraya, +32 authors Cynthia C Morton
  • Published in
    American journal of human…
    2008
  • Biology, Medicine
  • Apparently balanced chromosomal rearrangements in individuals with major congenital anomalies represent natural experiments of gene disruption and dysregulation. These individuals can be studied to identify novel genes critical in human development and to annotate further the function of known genes. Identification and characterization of these genes is the goal of the Developmental Genome Anatomy Project (DGAP). DGAP is a multidisciplinary effort that leverages the recent advances resulting… CONTINUE READING

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