Characterization of antineurofilament autoantibodies in Creutzfeldt-Jakob disease.

  title={Characterization of antineurofilament autoantibodies in Creutzfeldt-Jakob disease.},
  author={Shirin Bahmanyar and Ronald K. H. Liem and John Wesley Griffin and D. Carleton Gajdusek},
  journal={Journal of neuropathology and experimental neurology},
  volume={43 4},
The antineurofilament antibodies found in the serum of a chimpanzee with experimental Creutzfeldt-Jakob disease reacted specifically with the 200,000-dalton polypeptide of the purified neurofilament triplet. They also reacted strongly with thoroughly characterized neurofilament swellings of proximal axons of spinal cord motoneurons from beta,beta' iminodipropionitrile (IDPN)-intoxicated rats. 

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